tag:blogger.com,1999:blog-1629175743855013102.post1464170286823601160..comments2024-03-27T23:47:41.656-07:00Comments on Whole Health Source: Why Do We Eat? A Neurobiological Perspective. Part IStephan Guyenethttp://www.blogger.com/profile/09218114625524777250noreply@blogger.comBlogger38125tag:blogger.com,1999:blog-1629175743855013102.post-79570805263730260052013-02-16T12:09:52.304-08:002013-02-16T12:09:52.304-08:00You should read the following article - http://www...You should read the following article - http://www.cell.com/trends/neurosciences/fulltext/S0166-2236(13)00005-2nbchttps://www.blogger.com/profile/10753827916720600496noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-1763089765971480202012-11-04T08:52:54.520-08:002012-11-04T08:52:54.520-08:00What do you feel is the perfect diet for a 50 year...What do you feel is the perfect diet for a 50 year old male with metabolic syndrome (5 foot 11, 220 lbs)? The only diet I ever lost weight on was the Atkins diet, went all the way down to 189, but low energy levels a bit of non-normal depression had me off the diet after 5-6 months. The good news is I did not gain weight for almost a year (helped insulin resistance?) but then after a three years gained back to 210 lbs, then later 220. Want to diet much healthier this time and looking for some advice.Keith C. Collinshttps://www.blogger.com/profile/08832900605926066641noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-76909057757487306662012-10-12T08:39:17.115-07:002012-10-12T08:39:17.115-07:00Our everyday energy comes from food. And food come...Our everyday energy comes from food. And food comes with many varieties, and varies across every nation or continent. But given all the difference, we must all consider its true essence, and that is being healthy. We must always watch what we eat and prefer the healthier ones to maximize our body’s full potential and to boost our immune system.<br /><br /><a href="http://www.freshandhealthybrands.com/our-brands/yo-good/store-concepts-frozen-yogurt-franchise-for-sale.aspx" rel="nofollow">Joseph Carr</a>Joseph Carrhttps://www.blogger.com/profile/05000880698816717627noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-26232590469715806942012-10-12T05:43:17.512-07:002012-10-12T05:43:17.512-07:00@Sanjeev
Can't blame you for not wanting to he...@Sanjeev<br />Can't blame you for not wanting to hear about YET ANOTHER wretched hormone. As if there weren't enough already. Especially if you're eating white rice, let's say, and have convinced yourself that removing the manganese and magnesium isn't a problem. Janehttps://www.blogger.com/profile/18175128589806816624noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-57243022091369446042012-10-11T11:23:22.312-07:002012-10-11T11:23:22.312-07:00After all, how does one conclude insulin from carb...After all, how does one conclude insulin from carbs (but not protein) is the ONLY thing worth worrying about?<br /><br />Fallacy of composition: confusing a tiny part of the whole for the whole <br /><br />I fell for that one myself <br /><br />How did Lustig convince so many through that Youtube video that Fructose is poison? Partly through fallacy of composition. <br /><br />I didn't fall for that one. Sanjeevhttps://www.blogger.com/profile/09522727136330797375noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-68533513725515163412012-10-11T11:16:23.298-07:002012-10-11T11:16:23.298-07:00there are too many micro-mechanistic phenomena tha...there are too many micro-mechanistic phenomena that make no difference in the end when tested over the whole system over a reasonable time. <br /><br />It's basically the fallacy of composition and I've fallen for that stuff too many times in my life. <br /><br />Until there are multiple well controlled randomized controlled trials I'll give it a pass on changing my behaviour.Sanjeevhttps://www.blogger.com/profile/09522727136330797375noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-75278090218334109362012-10-11T04:49:00.096-07:002012-10-11T04:49:00.096-07:00@Sanjeev
The fact remains that an important satiet...@Sanjeev<br />The fact remains that an important satiety hormone (uroguanylin) works by activating an enzyme which is known to be dependent on manganese/magnesium. Therefore Mn/Mg are in some sense satiety signals. This does not mean hungry people seek out foods high in Mn/Mg, of course. Quite the opposite. But during our evolution it would have been difficult to avoid them.<br /><br />Uroguanylin is very new, and very hot. Here is a 2012 Nature News & Views article about it. Tell me if you can't get it, and I'll pick out some choice quotes for you. Or perhaps you can persuade Stephan to write a post about it.<br /><br />'Gastrointestinal hormones: Uroguanylin—a new gut-derived weapon against obesity?'<br />http://www.nature.com/nrendo/journal/v8/n1/full/nrendo.2011.206.htmlJanehttps://www.blogger.com/profile/18175128589806816624noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-55651836469254178912012-10-11T03:48:35.124-07:002012-10-11T03:48:35.124-07:00The very last paragraph regarding mice and dopamin...The very last paragraph regarding mice and dopamine I have a question about. Kenneth Blum in his studies showed that a lack of dopamine increased sugar cravings (http://www.springerlink.com/content/b475224658w86007/). IN my practice I have successfully used amino acid therapies such as tyrosine to mitigate food cravings in some people. Just curious as to what your thoughts are regarding that mice study showing that mice will eat less. Do mice not have non-homeostatic eating tendancies? Thanks a bunchAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-62127173016198868702012-10-10T12:19:39.376-07:002012-10-10T12:19:39.376-07:00to my reading it's almost a nonsequitur.
lac...to my reading it's almost a nonsequitur. <br /><br />lacking is proof that any of that is in any way linked to deficiencies. <br /><br />the comment reminded me of <a href="http://theness.com/neurologicablog/index.php/anomaly-hunting/" rel="nofollow"> this</a> <br /><br />copy & past for work safety:<br />http://theness.com/neurologicablog/index.php/anomaly-hunting/Sanjeevhttps://www.blogger.com/profile/09522727136330797375noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-46248049003227849522012-10-10T10:31:40.985-07:002012-10-10T10:31:40.985-07:00Stephan wrote, in response to Roger;
"There ...Stephan wrote, in response to Roger;<br /><br />"There are only a few nutrients that are known to be monitored by the body such that food preferences are adjusted accordingly. Salt is one of them, as you mentioned. As far as I know, it is not generally the case that people or animals will overeat to make up for nutrient-poor food. "<br /><br />I think this is a bit of an over-simplification. While this is true for most people, most of the time, there is one situation where it is not - that would be pregnant women. <br /><br />They are often driven to eat things they would not normally eat, and to not eat things that they do normally eat. And this changes in the different stages of pregnancy. Overall, they end up getting a very wide variety of micronutrients, much more than normal.<br /><br />This suggests to me that a system for nutrient based food preferences exists, but is not strongly active most of the time. I think (for non-pregant people) it comes into action only in response to a deficiency, and even then, some people, like vegans, train themselves to ignore/suppress the cravings.<br /><br />Pregnancy would seem to be a case of the body/brain being pro-active and not waiting for a deficiency.<br /><br />The well known effect of pregnant women having heightened taste/smell sensitivity shows the system can be up-regulated.Paul Nhttps://www.blogger.com/profile/11452852823080926838noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-9955659252607680992012-10-09T17:40:14.021-07:002012-10-09T17:40:14.021-07:00I am also curious about the dopamine mice, since s...I am also curious about the dopamine mice, since serotonin increasing drugs tend to suppress dopamine, which has the effect of suppressing sex drive and sexual sensation, but increases appetite and weight gain; whereas dopamine increasing drugs like amphetamines tend to reduce or eliminate appetite and in fact are often used for weight loss. The brain seems rather complex!stephershttps://www.blogger.com/profile/04753415893464809905noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-28391357322863398892012-10-07T23:59:05.884-07:002012-10-07T23:59:05.884-07:00Drclare offers the latest in non-surgical facial e...Drclare offers the latest in non-surgical facial enhancement. High quality medical aesthetic procedures at competitive prices.<a rel="nofollow">botox enfield</a> Discreet service, in private location, by a qualified medical doctor.Unknownhttps://www.blogger.com/profile/18219752249866341837noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-9086660644753496892012-10-07T17:05:15.920-07:002012-10-07T17:05:15.920-07:00Curious about the dopamine mice, since DA increasi...Curious about the dopamine mice, since DA increasing drugs promote leanness.chrishttps://www.blogger.com/profile/13655069520365178076noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-53590078129314216232012-10-06T17:09:38.397-07:002012-10-06T17:09:38.397-07:00Mary you said you increased your exercise but your...Mary you said you increased your exercise but your weight hasn't changed. Like you were questioning why. You didn't mention that you ate more.Suehttps://www.blogger.com/profile/03181442844616803097noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-46901932340049599702012-10-06T15:49:08.202-07:002012-10-06T15:49:08.202-07:00Dave, Sorry about your struggle with weight loss. ...Dave, Sorry about your struggle with weight loss. I can relate as I unsuccessfully tried to lose weight for over a decade. I never said that Gary Taubes had all the answers, or even the right answers, just that he persuaded me to try very low carb for a short time, about 2 weeks and that I could safely eat more saturated fat. Stephan persuaded me to eliminate grains though I do occasionally eat some white rice. I will probably add brown rice back using Stephan's soaking solution method, though I wish there was more than one study (done in China) on this method.<br /><br />I only lost 1-2 pounds during the very low carb 2 weeks, which was discouraging for me, because the anecdotal evidence was that I should have lost a lot more due to retaining less water. It took me 10 months to lose 30 pounds and I have been weight stable for the last 2 months. I still need to lose at least 10 more pounds and I feel stuck right now.<br /><br />Stephan, feels that very low carb should be done for only a short time, and that is what most of the low carb diets out there recommend. I suspect that cutting out the whole grains helped for 2 reasons: I may be sensitive to gluten and I eliminated the phytic acid and other anti nutrients in the bran of whole grains. I was already eating home cooked unprocessed food and all of the grains in my diet were whole. I have experimented with my diet composition and suggest you do the same. The safest carbs to add back are probably potatoes, sweet potatoes and white rice. Start off with a small amount with meat or fish. You may have to gradually rebuild your tolerance to glucose. <br /><br />Finally, there is a lot of individual differences and you need to experiment and find what will work for you. There is a lot of valuable info on this site and I recommend searching here using some of the labels. Good luck. <br /><br />Maryhttps://www.blogger.com/profile/04102798484661146655noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-50545257328325480192012-10-06T05:45:14.614-07:002012-10-06T05:45:14.614-07:00@Mary What would Gary Taubes say the answer is for...@Mary What would Gary Taubes say the answer is for me, a physically active person who can't shake about 20 lbs of unwanted fat even while on a ketogenic diet because while the diet worked to reduce hunger for about 6 months, that effect wore off and I regained some weight. His insulin hypothesis doesn't even begin to explain that.<br /><br />Not to mention the composition of my diet did have zero effect on my energy levels or my weight status. For my body a calorie really is a calorie except for the LC diet did have a temporarly appetite blunting effect, but it very well could have been from removing highly processed foods and/or increased protein.Grinchhttps://www.blogger.com/profile/09777059600105275295noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-32821395276442128762012-10-05T14:02:29.261-07:002012-10-05T14:02:29.261-07:00Before I get accused of being very low carb, I am ...Before I get accused of being very low carb, I am not. I eat vegetables, including potatoes, some fruit, meat and fish, and small amount of grass fed butter and aged cheese. I eat only a moderate amount of carbohydrate any one time. <br /><br />Before losing the weight, I had to have a snack before exercising or I would become shaky, sweaty, confused and hardly able to talk - all the symptoms of low blood sugar. This would also happen if I went too long between meals, forcing me to eat small amounts of food every 2 to 3 hours. Cutting calories, just left me lethargic, taking lots of naps due to the blood sugar crashes and I did not lose any weight. <br /><br />For me the key to losing weight was the diet change from low fat, moderate calories. I had to be convinced that increasing protein and saturated fat would not kill me. I would give a big part of the credit to Gary Taubes and his latest book and also to Stephan and other some other blogs. I know Gary is a dirty word on this blog. I know insulin is only part of the story, but since I have suffered with hypoglycemia my whole life, Gary's arguments resonated with me personally. I only did the very low carb diet for 2 weeks. My athletic performance suffered, which may have been do to the lack of glycogen. In addition, to the hiking, I do a strength building workout every other day, but I have been doing this and the hiking for many years. My hiking is on rutted dirt roads, trails and cross country and is over hilly terrain. It is more interval training since I hike uphill as fast as I can and coast downhill and the hills are steep. The morning hike and workout are done in the fasting state, before I eat and while my insulin levels are likely to be at their lowest. My goal is to make my metabolism efficient at switching back and forth between burning fat and glycogen.Maryhttps://www.blogger.com/profile/04102798484661146655noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-1533013140858179782012-10-05T12:33:40.563-07:002012-10-05T12:33:40.563-07:00Sue, You are kidding right? There was nothing &quo...Sue, You are kidding right? There was nothing "inadvertent" about my increasing calories with increased exercise, my appetite went up and I ate more.<br /><br />My neighborhood has plenty of overweight people walking daily or riding bikes and wondering why they aren't losing weight. I was one of them for many years. It took a diet composition change for me to lose over 30 pounds. I stopped eating whole grains, anything with added sugar in it and my daily beer with dinner. I increased protein and saturated fat. If anything the caloric density of my diet has increased and my calories consumed stayed about the same. My energy level is much better, I no longer have low blood sugar crashes daily and I sleep less. I have increased my leptin sensitivity, lowered my fat mass setpoint corrected my metabolism and lowered my fasting insulin. I would like to figure how to lower my setpoint by another 10 lbs. Stephan has a post on lowering the "setpoint".<br /><br />http://wholehealthsource.blogspot.com/2010/01/body-fat-setpoint-part-iv-changing.html<br />Maryhttps://www.blogger.com/profile/04102798484661146655noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-29759573550166533582012-10-05T10:57:40.415-07:002012-10-05T10:57:40.415-07:00Hi Katerina,
I'm not sure what you mean when ...Hi Katerina,<br /><br />I'm not sure what you mean when you say the setpoint idea has been "debunked". If you define the setpoint as a rigid number that is genetically fixed throughout life, then yes it's not correct-- but no one actually believes that version of it.<br /><br />If you define the setpoint as a loosely defended number that the brain attempts to bring the body back to after short-term changes in body fatness, then it is clearly correct. There is no doubt that the body 'defends' current fat stores against changes in the short to medium term, and there is also no doubt that this reflects the activity of relatively well-characterized homeostatic circuits in the brain. <br /><br />It would be absurd at this point to think that there is no mechanism in the body that defends against changes in fat mass, and so some version of the setpoint (or settling point, or whatever you want to call it) is going to be correct.<br /><br />But the level of fat mass that is 'defended' can be altered by a variety of circumstances, including diet, age, inactivity, drugs, and other factors. This is what trips people up when they think about the idea.<br /><br />Hi Jim,<br /><br />You're doing an uncontrolled experiment so it's hard to know what's having the effect. You're essentially going on a very low-calorie diet that's very simple/repetitive and mostly protein. Many people find that this kills their appetite. So I don't know if the effect has anything to do with the fermentable fibers.<br />Stephan Guyenethttps://www.blogger.com/profile/09218114625524777250noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-32396639566295048402012-10-04T21:54:01.194-07:002012-10-04T21:54:01.194-07:00Stephan, is it possible that our gut bacteria coul...Stephan, is it possible that our gut bacteria could be the most important driving force behind hunger? After all, they are the gatekeepers between food in our intestines and our bloodstream. And gut bacteria, like people, want to survive, which requires that they get the nutrients that feed them.<br /><br />It is well known that out gut microbes have many effects on our metabolism and our behavior. And since "good" microbes like bifidobacteria use fiber, it seems reasonable that they would initiate processes that would make their human hosts hunger for more fiber.<br /><br />For many years I have struggled with obesity and food cravings. Recently, I decided to try a little self-experiment to see if I could stop my food cravings by feeding inulin and FOS fiber to my gut bifidobacteria.<br /><br />I started on an extremely low-calorie diet (a few eggs daily), and I began taking VSL #3 probiotic capsules, and Jarrow inulin/FOS powder.<br /><br />The results were fascinating, and exactly what I had hoped: my hunger stopped, my blood pressure dropped, my diabetic blood sugar readings improved, and my weight is dropping nicely.<br /><br />Does it make sense that all these developments could have been caused simply by feeding inulin and FOS fiber to my gut bacteria?jimpurdy1943@yahoo.comhttps://www.blogger.com/profile/12974301744118775363noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-74476563127692971382012-10-03T19:13:57.938-07:002012-10-03T19:13:57.938-07:00Mary, do you know how many calories you eat. Coul...Mary, do you know how many calories you eat. Could be that you gain weight with sugary foods because they tend to be more calorie rich and you eat more of them. <br />When you increased your exercise you may have inadvertently increased calories consumed and hence no weight loss.<br />Suehttps://www.blogger.com/profile/03181442844616803097noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-6594512983356451882012-10-03T16:40:12.594-07:002012-10-03T16:40:12.594-07:00To Stephan: you use the term "setpoint" ...To Stephan: you use the term "setpoint" but I was taught that the setpoint theory had been debunked, because of several problems. Are you just using this as a general term? <br /><br />By the way, some of you might be interested in this post:http://katerinabent.blogspot.com/<br />I talk about a few interesting research studies done on hunger and eating. Anonymoushttps://www.blogger.com/profile/03880517909789826463noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-41037921764242890452012-10-03T14:55:18.873-07:002012-10-03T14:55:18.873-07:00Actually, I should clarify the above; when I regul...Actually, I should clarify the above; when I regularly eat anything with more than a very small amount of sugar in it, I gain weight. I also limit my fruit consumption to a small amount at any one time.<br /> <br />Thanks Stephan, I find this blog very valuable.Maryhttps://www.blogger.com/profile/04102798484661146655noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-40398164866303793762012-10-03T14:30:29.679-07:002012-10-03T14:30:29.679-07:00Sue,
Because of a schedule change a month ago, I ...Sue,<br /><br />Because of a schedule change a month ago, I have increased my morning hiking to around 25 miles per week from 10 miles. Has my weight changed? No, it has stayed within the same 2 lb weight band as before. Likewise, if I go out and have an unusually large meal, I can hardly sleep that night because I will be hot. I have found that if I avoid all sweets during the holiday period and just eat the meats and cheeses, I will not gain the 2 to 3 lbs I used to. I know this is just a n=1.<br /><br />Recently, I decided to have a slice of chocolate cheesecake when I ate out - I rarely eat sweets. Talk about hyper-palatable, I was craving more cheesecake for several days. This is what I think Stephan will get into. You cannot gain weight unless something drives your fat setpoint higher and that will be hyper-palatable food. I find sweets are that for me and I gain weight when I eat them.Maryhttps://www.blogger.com/profile/04102798484661146655noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-48890742898800412622012-10-03T12:40:19.284-07:002012-10-03T12:40:19.284-07:00Mary and Sue can both be right.
If abnormal omega ...Mary and Sue can both be right.<br />If abnormal omega 6:3 ratios are driving excess caloric consumption, and those calories tend to be fructose and glucose to begin with, then we can ALL be right. <br />We really do have a mixed model that accommodates FRH, CICO and CIH, and also includes: microbiota; fructose, seed oil and grains as food toxins; and any other sane suggestions that might be forthcoming and that aren't contradicted by the evidence. <br /><br />"instead of thinking outside the box, think about the box".Puddleghttps://www.blogger.com/profile/00953398103675945541noreply@blogger.com