tag:blogger.com,1999:blog-1629175743855013102.post147572752445749845..comments2024-02-25T02:24:14.972-08:00Comments on Whole Health Source: Drug Cessation and Weight GainStephan Guyenethttp://www.blogger.com/profile/09218114625524777250noreply@blogger.comBlogger100125tag:blogger.com,1999:blog-1629175743855013102.post-52482782147776874162014-12-18T01:02:28.053-08:002014-12-18T01:02:28.053-08:00Great Post, I love to read articles that are infor...Great Post, I love to read articles that are informative and actually have good content. Thank you for sharing your experiences and I look forward to reading more.Anonymoushttps://www.blogger.com/profile/11173834832464463296noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-49103450568801931952014-02-27T08:45:28.644-08:002014-02-27T08:45:28.644-08:00Ive been clean from methamphetamine for 6 months. ...Ive been clean from methamphetamine for 6 months. My longest clean time was 5 years and got a degree in fitness technology. Ive been addicted to the drug. For 14 years. The drug kept me effortlessly thin throughout most of my use but the last 5 years it was not as affective. I have found very little information on why. What I did find was that my metabolism must have gotten so badly tapped out and familiar with the drug that it just didnt have the same effect. I'm extremely obsessed with body image. Gaining even more weight now that I'm clean again has put me in constant depression. What I have learned is the my metabolism was in starvation mode and was losing muscle mass. Muscle burns fat. With less muscle the body is going to need to take in even less calories and exercise even more. trying to count calories and exercise the way in normal person wouldn't want to lose weight would be ridiculous. Instead I need to be patient and eat nutritious healthy meals focusing on my proteins and building muscle mass by exercise.Anonymoushttps://www.blogger.com/profile/03947930845642190685noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-63433545432406529432013-02-16T03:01:32.559-08:002013-02-16T03:01:32.559-08:00Excellent post,thanks for sharing this.If you are ...Excellent post,thanks for sharing this.If you are suffering from <a href="http://www.youtube.com/watch?v=OxYy6LcssUY" rel="nofollow">binge eating</a> disorder, please have the guts to accept and confess to your family members that you are facing problems.Anonymoushttps://www.blogger.com/profile/13491933823026420021noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-75056633895399938812011-07-30T18:26:03.848-07:002011-07-30T18:26:03.848-07:00I chain smoked for 7 years, quitting at age 22. Wh...I chain smoked for 7 years, quitting at age 22. When a smoker, I had over the years gradually slimmed slightly from my pre-smoking 15-year-old, despite eating fast food through my teens. In college, I would have coffee and cigarettes for breakfast, go to school, smoking all the way, and then finally eat when I got to work at 3PM, sometimes not till the evening. Not eating was a matter of time and not really caring about food. But once I ate, I was starving and it was something huge, but that was all I'd have until the next day. It was like a fiend's Warrior Diet.<br /><br />Anyway, when I quit, I remember how shocked I was that _within the month_ I couldn't zip up my pants. I also noticed how food was now crossing my mind -- I would crave it -- and I could order a sandwich, a side salad, and a platter of that pre-made sushi all for lunch. I started getting muffins on campus during the day; and stopping off to order out Chinese food to eat before work. Granted I wasn't "fat", but I wasn't the slim little thing I was used to being. I definitely was needing a better fitting wardrobe. What I brought away from all this was that cigarettes are a potent appetite suppressant. Food went from a back-burner issue to something I always wanted.<br /><br />(I'm not starving hungry anymore, years later, but I've only attained that skinnier figure that I had before--albeit with better muscular development--by eating primal.)Catthttps://www.blogger.com/profile/14109018483236614477noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-62396505981403451002011-07-12T13:48:53.330-07:002011-07-12T13:48:53.330-07:00Stephan,
On your point about “ I don't necessa...Stephan,<br />On your point about “ I don't necessarily think all or even most obese people are "addicted to food",” I was wondering what you made of the research from the Griesel’s regarding heavily processed foods being addictive because the added chemicals trigger the same kinds of brain activity seen in substance dependence?<br />http://www.dailyrx.com/news-article/modern-foods-contain-combination-added-chemicals-may-create-cravings-12560.html<br />Thank you @Beth for all the great follow up reads!Steph Rhttps://www.blogger.com/profile/09908143304628733531noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-90054261888064487732011-07-10T04:28:15.593-07:002011-07-10T04:28:15.593-07:00How about sibutramine and the drugs that contain i...How about sibutramine and the drugs that contain it? i know that sportsmen use it but it is illegal so, what if you want to buy it and use it would it do something bad to you? i mean it says you should exercise a lot but what if you dont? also what do you think about those drugs and pills that you take as meal replacements? i saw some on http://biggestloserclub.com.au/ but i'm not sure if they will help me lose weight fast...did any of you use something similar?AlexandraMMRhttps://www.blogger.com/profile/14892777410562305018noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-84666989247113981742011-07-08T00:09:25.734-07:002011-07-08T00:09:25.734-07:00ItsTheWooo2 - It was Bromocriptine (Parlodel). Inc...ItsTheWooo2 - It was Bromocriptine (Parlodel). Increased my appetite and gained a few pounds, but calorie partitioning was favorable. It's been shown in studies to increase insulin sensitivity and was re-branded a a T2 diabetes drug in recent years.Yveshttps://www.blogger.com/profile/11735725235746572417noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-33926047281321142052011-06-29T22:03:19.494-07:002011-06-29T22:03:19.494-07:00If it were so simple -
Please realize that we hav...If it were so simple -<br /><br />Please realize that we have the following:<br /><br /><br />Precursors:<br /> <br />L-Phenylalanine → L-Tyrosine → L-DOPA → Dopamine.<br /><br />But Phenylalanine and Tyrosine are not addictive foods...karlhttps://www.blogger.com/profile/13490274388549702613noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-61342151199857380452011-06-29T11:26:02.925-07:002011-06-29T11:26:02.925-07:00I wonder how the cycle of hormones over the course...I wonder how the cycle of hormones over the course of a day might play into this? In general I find food to be far less "rewarding" (tempting) in the AM, which makes intermittent fasting easy for me. I can comfortably go til 1 or 2 pm without consuming anything but a cup of coffee black or with cream. At lunch time I want a good dose of protein and fat. But come evening, the carb and alcohol cravings sometimes hit hard. Carbs and alcohol seem to be somewhat interchangeable to me. Last night I had a plate of nachos and a glass of wine... if not for the nachos I might have needed 2-3 glasses to be satisfied.Larkhttps://www.blogger.com/profile/00311338401075062323noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-38394415971846279162011-06-28T20:34:25.725-07:002011-06-28T20:34:25.725-07:00Yves - I am curious what dopamine agonists you hav...Yves - I am curious what dopamine agonists you have taken that increased appetite.<br /><br />Multiple factors can operate at once; just because dopamine agonists are promoting weight stability does not necessarily mean any drug that raises dopamine should reduce weight. If the drug is antihistamine, or if it raises serotonin more than it does dopamine, or if it is a dopamine agonist-antagonist, weight gain may occur. <br /><br />For example, if someone is on seroquel (very fattening serotonin dopamine antagonist + antihistamine) but adds in wellbutrin (dopamine/norepinephrine boosting) they may gain weight... but it's not because of the wellbutrin its the seroquel.ItsTheWooohttps://www.blogger.com/profile/12057537399918684119noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-38160662968500174932011-06-28T20:30:57.363-07:002011-06-28T20:30:57.363-07:00Heterosexual / sexually typical male animals with ...Heterosexual / sexually typical male animals with amygdala problems are not homosexual - their inability to mate with females is not because of a lack of sexual interest (and an interest in males) , its because of a fear/freeze/depressive response suppressing sexual behavior. <br /><br />This would be like a heterosexual person who is traumatized refusing to have sex (e.g. sexual abuse victim). This is NOT homosexuality. <br /><br />Homosexuality features normal sexual motivation/interest, however the sexual interest is incongruent with primary sex characteristics. <br />Scientists can and have created same-sex preferring animals by manipulating prenatal sex steroids hormones at certain periods of development prenatally.ItsTheWooohttps://www.blogger.com/profile/12057537399918684119noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-17948178841232078242011-06-28T20:04:31.057-07:002011-06-28T20:04:31.057-07:00I should also clarify that it is possible for the ...I should also clarify that it is possible for the external body to appear sex congruent (normal male or female anatomy) but the brain may be feminized or masculinized in an opposite direction of the genitals.<br /><br />Depending on the timing of the hormone fluctuations, a child may have normal male (or female) anatomy, but the brain structure is sexually ambiguous and highly feminine (or masculine). The child will grow up a boy but feel like a girl and have a sexual response/interest to males. These are transsexual/gendered people.<br /><br />There is a psychological component to sexual and gender behavior, but the research is pretty clear that male and female brains are anatomically different and transsexuals/homosexuals show ambiguity in their brain structures.<br /><br />It is no different than an intersex condition (hormone abnormalities resulting in the primary sex characteristics being "in between" not fully male or fully female)... the only difference is that the brain is MUCH more sensitive than the external body, and it is relatively easy to induce some type of gender or sexuality incongruency with relatively mild low level hormone fluctuations. It is much more rare to be intersex because that requires a very severe hormone disorder prenatally.ItsTheWooohttps://www.blogger.com/profile/12057537399918684119noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-42617872045293287422011-06-28T19:56:29.718-07:002011-06-28T19:56:29.718-07:00Homosexuality is not a brain disorder, typically i...Homosexuality is not a brain disorder, typically it is the result of endocrine abnormalities pre and early post natal. <br /><br />Females with adrenal disorders which result in higher than normal levels of androgens before birth are more frequently lesbian or masculine behaving exhibiting lower levels of stereotypically feminine behaviors. CAH is a genetic disease where the enzyme to synthesize cortisol frm its precursor is partially or totally nonfunctional. The precursor increases, which the body shunts into testosterone synthesis. Females with this genetic disorder can develop sexually ambiguous genitalia, and about 50% develop into lesbian or bisexual adults.<br /><br />Males who are exposed to very high levels of testosterone may experience paradoxical feminizing of the brain. This is the "younger brother effect" - males with a lot of older brothers are more frequently homosexual, because each brother exposed to higher and higher levels of testosterone during development. <br />It is believed that the maternal immune system reacts to the testosterone after each male birth; it may be that this immune reactivity is increasing testosterone in the body but preventing it from affecting the fetal brain the way it sh9ould.<br /><br /><br />Anyway, homosexuality and gender identity atypicalities are not "brain disorders", but they are the symptomatic result of having been exposed to abnormal hormone levels or abnormal hormone binding before birth or shortly after birth as this is when gender and sexual orientation are programmed.<br /><br /><br /><br />I disagree strongly with mitochondrial's view that oxytocin and being "super friendly/super bonding" will cause homosexuality. This is extremely unlikely; most likely there is hard-wired area(s) of the brain responsible for sexual interest and sexual response and sexual behavior, which is sexually dimorphic between males and females. Being exposed to high testosterone vs high estrogen determines how these areas develop, and thus, whether you are attracted to masculine people or feminine people, whether you want to have a lot of sex with many partners or a little with few partners, whether you initiate sex or are feminine/passive, etc. <br /><br /><br />Just like we are born with mental "hardware" that can instantly recognize a human face - and remember it - we are also born with mental "Hardware" that can detect signs of femininity or masculinity and respond with sexual arousal and interest. <br /><br />whether or not one develops "masculine" sexual mental hardware or "feminine" sexual mental hardware depends on the hormone situation in their brain before /shortly after birth... the same structures differentiate into either male or female ones, just as our gonads differentiate into either ovaries or testicles, or a clitoris vs penis, etc.ItsTheWooohttps://www.blogger.com/profile/12057537399918684119noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-32262364481456183812011-06-28T19:56:00.189-07:002011-06-28T19:56:00.189-07:00Malpaz - regarding how you relate to my descriptio...Malpaz - regarding how you relate to my description of what I go through and my perception perhaps serotonin may be too dopamine suppressive in my brain...<br /><br />Well the way I deal with it is I eat a low carbohydrate diet, which I find allows me to eat calories without feeling tired and dim and depressed the way I do on starch and sugar. If I eat a high fat diet, I feel similar to how I do when I don't eat... energetic and alert.<br /><br />I can't at all relate to "normal" people when they say low carb diets make them depressed. I can't realte to "normal" people who eat food for comfort, people who feel good after eating brownies and ice cream. NEVER experience that.<br /><br />I only feel "happy and good' when I drink coffee, avoid starch/sugar, eat moderately of a low carb high fat diet. Coffee makes me feel like food restriction. Low carb moderate energy diets do as well. <br />High carb and high calorie makes me feel polar opposite - depressed, tired, dim, dead.<br /><br />My advice to you would be to avoid carbs like the plague; you can retain some of the cognative/emotional benefits of starving without requiring malnourishment.ItsTheWooohttps://www.blogger.com/profile/12057537399918684119noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-26549922440005172522011-06-28T12:04:52.156-07:002011-06-28T12:04:52.156-07:00This comment has been removed by the author.Might-o'chondri-ALhttps://www.blogger.com/profile/17572208303795253605noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-41903572171343134212011-06-28T09:46:06.726-07:002011-06-28T09:46:06.726-07:00I, like you, have virtually no sugar cravings thes...I, like you, have virtually no sugar cravings these days. I can sit in front of a dozen donuts and be bored out of my mind and not eat them either. They just simply do not interest me. Not even for a split second.<br /><br />If it was berries then that would be different. Sure, its sugar, but its also nutrition.<br /><br />A rewarding food for me is 70-99% dark chocolate. But, I can only handle a block or 2 at a time due to the high phytic acid content.Primal Toadhttps://www.blogger.com/profile/13330919403143835896noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-55953084234233805152011-06-28T07:56:01.647-07:002011-06-28T07:56:01.647-07:00Nice article
really I like it :)Nice article<br />really I like it :)Gianhttps://www.blogger.com/profile/07530083456193033025noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-17915964411982870002011-06-28T06:25:18.084-07:002011-06-28T06:25:18.084-07:00mem, I found via a comment he wrote on the previou...mem, I found via a comment he wrote on the previous post that "John" is actually Dr. Jack Kruse, who is blogging here: http://jackkruse.comBeth@WeightMavenhttps://www.blogger.com/profile/17725838221780385439noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-51360457135275939712011-06-28T05:34:37.586-07:002011-06-28T05:34:37.586-07:00hello, thanks for the important information.. it i...hello, thanks for the important information.. it is really a point of concern.. thank you.. <br /><br />regards,,<br /> <a href="www.astermeds.com" rel="nofollow">astermeds.com</a>Joshuahttps://www.blogger.com/profile/00497356256486063942noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-29914016343407159032011-06-28T01:33:11.265-07:002011-06-28T01:33:11.265-07:00Some of my own n=1 experiments to throw a monkey w...Some of my own n=1 experiments to throw a monkey wrench. I found when I was on dopamine agonists, they not only increased appetite (they're suppose to, if anything, decrease appetite), but made me gravitate towards sweets. <br /><br />Also, lately I've been eating ice cream liberally but rounding it out with a nutritious diet. No weight gain or increased caloric intake despite 20-30% calories coming from ice cream. I think the danger of the junk foods isn't so much the palability, but that the easily and quickly absorbed calories may be metabolically stimulating in the short run (as the body responds to a surge in calories) but runs up a "nutrient debt" that triggers the body to eat again. It's probably this phenomonom that blows the feedback mechanism that would put a check on appetite. If you could make a meal of potatoes, liver, and spinach taste, smell, look, and feel like eating dorritos, cake, or whatever, I would be willing to bet people would simply not develop the pathology people are talking about.<br /><br />All the examples of drugs and junk food do exactly that, the send a signal that the body is "fed" without actually feeding the body. The body responds my desensitizing itself to the stimulate and you get a vicious cycle. I think, and my own short term observations confer, you can eat a lot of 'addictive' foods if you fill the gaps with super nutrient-dense foods like liver, greens, etc. and exercise.Yveshttps://www.blogger.com/profile/11735725235746572417noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-90237314481884611662011-06-27T18:00:05.705-07:002011-06-27T18:00:05.705-07:00mitochondrialal... after reading your last comment...mitochondrialal... after reading your last comment, i got a weird thought but wouldnt what you said also make someting like homosexuality a brain disorder?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-34602952425170206002011-06-27T17:16:08.044-07:002011-06-27T17:16:08.044-07:00This comment has been removed by the author.Might-o'chondri-ALhttps://www.blogger.com/profile/17572208303795253605noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-22229272062187001202011-06-27T16:28:08.506-07:002011-06-27T16:28:08.506-07:00Stephan, not sure if you've come across this i...Stephan, not sure if you've come across this in your travels, but it's a paper relevant to this thread (also from the collection mem pointed to): <a href="http://www.psych.med.ufl.edu/aec/research/abstracts/bmibiopsych.pdf" rel="nofollow">Weight gain after adolescent drug addiction treatment and supervised abstinence</a>. FYI!Beth@WeightMavenhttps://www.blogger.com/profile/03821749502002515139noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-12149436008783848272011-06-27T15:57:58.875-07:002011-06-27T15:57:58.875-07:00Hi Everyone,
Nice discussion. I've been foll...Hi Everyone,<br /><br />Nice discussion. I've been following the comments but I won't be able to respond to them individually this time. I particularly appreciate the firsthand accounts that several people offered about how they reacted to drug cessation.<br /><br />A few people made the comment that some of the post-cessation weight gain could simply reflect returning to a normal weight, which is a good point. Still, I think the evidence from drug use fits the hypothesis that reward (including non-food reward) can influence body fatness. I find it interesting that people seem to seek alternative forms of reward after drug cessation, implying that we really do seek a certain amount of reward out of each day.Stephan Guyenethttps://www.blogger.com/profile/09218114625524777250noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-40528417775091532812011-06-27T14:31:24.482-07:002011-06-27T14:31:24.482-07:00Kris makes a great point. All of these drugs (incl...Kris makes a great point. All of these drugs (including caffeine) has the same effect as junk food, at least if we believe the studies on mice and rats. One of those studies on mice cited above showed a similar effect on dopamine and its receptors with a combo of sugar+fat as drugs. Of course, nothing like illicit drugs, but still pointing in that direction.<br /><br />By quitting the illicit stuff one also becomes more sensitive (after withdrawal) which would mean that legal drugs like coffee would start to be rewarding (until that option is exhausted), and - of course - also junk food due to its high calorie fat+sugar combo.Michel Blomgrenhttps://www.blogger.com/profile/02456543461959578400noreply@blogger.com