tag:blogger.com,1999:blog-1629175743855013102.post2098801400582879926..comments2024-02-25T02:24:14.972-08:00Comments on Whole Health Source: The Diet-Heart Hypothesis: Subdividing LipoproteinsStephan Guyenethttp://www.blogger.com/profile/09218114625524777250noreply@blogger.comBlogger118125tag:blogger.com,1999:blog-1629175743855013102.post-62912305141052745862010-05-21T07:59:19.100-07:002010-05-21T07:59:19.100-07:00"There lots of published evidence to this eff..."There lots of published evidence to this effect. It seems that when lipolysis increases and serum FFA increase insulin sensitivity is much reduced. The question is if this has anyn long term negative effect."<br /><br />The writer of this comment believes that diabetics (carbohydrate intolerant, by definition) should eat more carbs.<br /><br />There may however be something to this: if I eat too many carbs and spike my BG, and eventually my insulin, I suffer from an increased insulin resistance which lasts for several hours.<br /><br />How do I know? My BG shows raised on my meter but my muscles don't get any energy, so I assume the Glut-4 transporters shut down.<br /><br />The time scale over which this occurs is not dissimilar to the time it takes to break the carbs down into trigs and get them into the blood and then manipulate the fats into store.<br /><br />The exact opposite happens when I eat fats: the BG and insulin don't shift and my energy level stays up. Doing this long term until my body has adapted to fat/ketones rather than glucose as primary fuel has removed all my reactive hypoglycemia symptoms along with the hyperglycemia.<br /><br />All of my lipid panels are in agreement that the lipids *in my blood* are raised by carbs, not dietary fat. This is undoubtedly one reason why most diabetics find insulin resistance drops dramatically from carbohydrate reduction. My trigs/HDL ratio fell (US numbers) from over 15 to around unity from carbohydrate reduction. Not at all uncommon.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-89036411168842503052009-08-08T02:07:35.272-07:002009-08-08T02:07:35.272-07:00Aaron:
You wrote:
"I mainly wrote my comments...Aaron:<br />You wrote:<br />"I mainly wrote my comments to address people who are on 20grams or less of carbs a day-- i just don't think its a grood idea. I would assume your liver would be working overtime to process protein into glycogen (from food or your muscles).<br /><br />I have always had this hunch that when you use stored glycogen in your muscles for fuel instead of fat-- you are bypassing some of the byproducts that are made during fat oxidation for fuel-- I wonder if there are any studies that have looked at this (do you know of any Stephan?)<br /><br />I know that mitochondria get better at processing fat byproducts the higher your reliance on fat as a fuel source-- by why not just try to use carbs as a clean source-- if i am right that there are less byproducts."<br /><br />Basic biochemistry will put your worries to rest.<br /><br />If you're concerned about ROS and other radicals - the question is not settled. However, glucose oxidation has higher radical generation potential than beta-oxidation. The reason is two-fold: a) Unlike beta-oxidation glycolysis involves a lot of reactions featuring the generation of radicals as a part of the reaction mechanism. Rarely these highly reactive intermediates dissociate from the enzyme and can damage cellular components (glycolysis is located in the cytoplasm). <br />b) Glucose oxidation produces a higher NADH/FADH2 ratio. What this means is that Complex I feeds more electrons into the electron transport chain compared to beta-oxidation. Complex I is the main site of premature electron leakage to oxygen and thus ROS generation.<br /><br />As for the liver-gluconeogenesis thing - no, on a ketogenic diet body's need for glucose is reduced down to 30-50g per day (based on your body weight) and the liver is capable of producing many times more in 24h.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-7569175769963678182009-08-07T12:20:48.445-07:002009-08-07T12:20:48.445-07:00By the way, I'm skeptical that overweight is t...By the way, I'm skeptical that overweight is the healthiest weight. I acknowledge that in observational studies, risk of death is often lower in people who are overweight than in those who are obese and thin. I also acknowledge that a person can be overweight and athletic.<br /><br />But overweight is not the natural state for our species. It's largely a product of industrial society. Even 40 years ago in the US, overweight and obesity were less prevalent. I suspect that the true optimum is to be rather thin. I'm not taking about rail-thin, because you do see hunter-gatherers with some body fat, but BMI over 25? I'm skeptical that it's the true optimum.Stephan Guyenethttps://www.blogger.com/profile/09218114625524777250noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-42941242075061417332009-08-07T12:16:13.683-07:002009-08-07T12:16:13.683-07:00Bris,
Thanks for the clarification about BF%.
...Bris,<br /><br />Thanks for the clarification about BF%. <br /><br />My goal is not to maintain an identical level of fitness until I'm 80. It's to avoid chronic disease, feel good and remain functional. Slow decline in fitness is inevitable, but it's possible to remain very fit until 70 and beyond.Stephan Guyenethttps://www.blogger.com/profile/09218114625524777250noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-43238173363944948022009-08-07T07:29:39.904-07:002009-08-07T07:29:39.904-07:00Bris,
I don't think the scale was perfectly a...Bris,<br /><br />I don't think the scale was perfectly accurate but I did see, using the same scale, my body fat go from 14 to 7 to 4. General trend of going down.<br /><br />Breakfast: 5-8 Bacon strips 3 Eggs, Tablespoon coconut oil.<br /><br />Lunch: Between 300-500grams regular ground veal in homemade tomatoe sauce that includes a stick of butter.<br /><br />Snack: Large handfull almonds, tablespoon coconut oil.<br /><br />Dinner:700Grams of Capless Rib Steak(eating all the fat)<br /><br />Snack: Broccoli dipped in 50-75ml of EVOO.darnoconradhttps://www.blogger.com/profile/15168444082336519012noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-42066638797683065512009-08-07T04:26:24.880-07:002009-08-07T04:26:24.880-07:00Sorry I thought Cunnane meant ocean shores not lak...Sorry I thought Cunnane meant ocean shores not lake shores - negative comment withdrawn.<br /><br />I am studying a postgraduate exercise science programme. Exercise scientists don't consider weight, body fat or cholesterol to be very important for health. Their argument is that <i>fitness is much more important than fatness</i>. In fact it is possible to be a exceptionally healthy and very fit with a BMI of 35. Most of the male exercise science faculty at my university are above average weight and not particularly lean.Brishttps://www.blogger.com/profile/05771534538377496202noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-34943311646169129102009-08-07T03:59:32.112-07:002009-08-07T03:59:32.112-07:00darnoconrad
I would be very concerned about your...darnoconrad <br /><br />I would be very concerned about your weight. You are at least 10kg underweight and on the borderline of anorexia. Your original weight of 183lb was probably about right. <br /><br />There is absolutely no evidence that either male body fat levels <15% or low BMI confer any health advantages. In fact most male exercise scientists have a BMI >25 and average body fat levels. <br /><br />There is ample evidence that very low body fat levels cause severe endocrine disruption and osteoporosis. Osteoporosis is irreversible.Brishttps://www.blogger.com/profile/05771534538377496202noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-55151402500872742282009-08-07T03:43:07.819-07:002009-08-07T03:43:07.819-07:00Bris,
;-) Always nice to disagree.
Have you read...Bris,<br /><br />;-) Always nice to disagree.<br /><br />Have you read 'Survival of the fattest' by Cunnane?Melchior Meijerhttps://www.blogger.com/profile/12416984522705147485noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-12860856292811935772009-08-07T03:33:56.453-07:002009-08-07T03:33:56.453-07:00Now that this thread has drifted off so completely...<i>Now that this thread has drifted off so completely, what do you think of the idea that all these typical human changes are an adaptation to a coastal environment, as proposed by Hardy</i><br /><br />Complete and utter rubbish. We evolved from tropical jungle dwelling frugo-insectovores who lived nowhere near coasts. Apes dislike water and will never immerse their heads. Untrained humans are probably the <i>worst</i> swimmers of any mammal species (except apes).Brishttps://www.blogger.com/profile/05771534538377496202noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-2718897245504059782009-08-07T02:53:04.331-07:002009-08-07T02:53:04.331-07:00Bris,
And, although one would not always suspect ...Bris,<br /><br />And, although one would not always suspect it, a much bigger brain. Now that this thread has drifted off so completely, what do you think of the idea that all these typical human changes are an adaptation to a coastal environment, as proposed by Hardy, Morgan and Cunnane? The Coastal Dweller Theory is often ridiculed, but in my humble opinion it's the best explanation available.Melchior Meijerhttps://www.blogger.com/profile/12416984522705147485noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-36290902230937848052009-08-07T01:21:33.030-07:002009-08-07T01:21:33.030-07:00Aaron:
I love it if there was some food source tha...Aaron:<br /><i>I love it if there was some food source that was primary short chain fatty acids-- then we could duplicate the fatty acid profile other primates have.</i><br /><br />Why? Just because two species are related doesn't mean they require similar diets:<br /><br />- Polar bears evolved from Brown bears only 200,000 years ago but they have very different diets. <br /><br />- Giant Pandas are also bears but their diet is 98% bamboo. <br /><br />- Gelada baboons only eat grass.<br /><br />Non-human primates derive their short-chain fatty acids mostly from gut fermentations of cellulose-rich plant matter rather than direct dietary intake. <br /><br />Humans have had around 5 million years of severe evolutionary pressure to eat a quite different diet to other primates. eg. humans in contrast to chimpanzees have:<br /><br />- very poor cellulose tolerance<br /><br />- a much smaller colon <br /><br />- a larger ileum<br /><br />- much smaller teeth<br /> <br />- far weaker jaw musculature<br /> <br />- 10x as much salivary amylaseBrishttps://www.blogger.com/profile/05771534538377496202noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-42628078659127803372009-08-07T00:23:13.994-07:002009-08-07T00:23:13.994-07:00darnoconrad:
I'm on a low carb diet. I don'...darnoconrad:<br /><i>I'm on a low carb diet. I don't count exactly but my only source of carbs is some veggies which I do not think amount to more than 10grams a day.</i><br /><br />You won't get <10g/day carbs unless you are living on meat and black coffee. A cup of regular milk has 10g of carbs. Even a small amount of vegetables will get normally put you you over the 50g/day mark.Brishttps://www.blogger.com/profile/05771534538377496202noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-47379215292605295692009-08-07T00:03:39.766-07:002009-08-07T00:03:39.766-07:00darnoconrad:
If you had 4% body fat you would eit...darnoconrad:<br /><br />If you had 4% body fat you would either be in a morgue or in a hospital on life support. Only a handful of world class athletes have ever been found to have as low as 6% body fat. That is only ever for a few days during competition. The only way to measure body fat accurately is with a DXA scan which costs about $200. <br /><br /><br />Stephan:<br /><br />Abdominal muscles are often very well defined at 12-14% body fat. At 10% body fat you can see most subcutaneous veins and arteries clearly.<br /><br />I didn't say that people under 35 are fit. I said it is much easier to stay fit when you are under 35. World record performance falls about 1% per year after age 35.Brishttps://www.blogger.com/profile/05771534538377496202noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-50040444255283617222009-08-06T11:41:04.611-07:002009-08-06T11:41:04.611-07:00Aaron a high fat diet very actively favours lactic...<i> Aaron a high fat diet very actively favours lactic acid bacteria not putrefactive bacteria (which require carbohydrate). Liquid elemental diets containing 80% fat:20% protein with no carbs/fibre are currently being used to treat severe Irritable Bowel Disease. </i><br /><br />really? This is almost the exact opposite of what i have "thought" i've read-- do you have any studies to back this up?<br /><br />I love it if there was some food source that was primary short chain fatty acids-- then we could duplicate the fatty acid profile other primates have.<br /><br />My other question question still stands-- is there any studies out there to show if using carbohydrates for energy creates less byproducts in compared with fat metabolism. In terms of not generating as many free radicals.Aaronhttps://www.blogger.com/profile/14565481105849556142noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-74475907728825405702009-08-06T08:43:22.942-07:002009-08-06T08:43:22.942-07:00Bris,
You said "It is quite easy to stay hea...Bris,<br /><br />You said "It is quite easy to stay healthy and in shape when you are young. After age 35 it becomes much harder." <br /><br />I have to disagree. Most people my age (29) are not healthy or in shape. I'm not showing any of the metabolic precursors to outright dysfunction that you see in the general population, such as central adiposity, insulin resistance, poor glucose control, high blood pressure, etc. <br /><br />"there is no way you are 7% body fat."<br /><br />Maybe so, but I'm not attached to the number in any case. I can see my abdominal muscles so I have very little fat, whatever the actual number is.Stephan Guyenethttps://www.blogger.com/profile/09218114625524777250noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-41393042690600803622009-08-06T07:00:55.941-07:002009-08-06T07:00:55.941-07:00I'm on a low carb diet. I don't count exac...I'm on a low carb diet. I don't count exactly but my only source of carbs is some veggies which I do not think amount to more than 10grams a day.<br /><br />When I started low carbing I was about about 14-16 percent body fat, over time I went down to 10, 7, and my last reading was 4 percent. You can make what you want of that. I imagine there may be some inaccuracies with the scale but all other people using it have remained at the same body fat level. 6'3, 153LBS. Went down from 183LBS.darnoconradhttps://www.blogger.com/profile/15168444082336519012noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-11768284209177592022009-08-06T00:52:40.697-07:002009-08-06T00:52:40.697-07:00Stepahan:
I do like how much more convenient it is...Stepahan:<br /><i>I do like how much more convenient it is to eat carbs. I feel hunger more than I did on low-carb, but I can still skip meals just fine. I'm probably eating about 52% fat, 35% carbohydrate, and 13% protein, but I never count. Roughly 3,500 calories a day. 5'9", 153 lbs, 7% body fat. That's 300 g carbs per day. I have no regard for glycemic index, I'll slam potatoes like the antidote's in them. My appetite goes way down when I'm not strength training, bike commuting, etc.</i><br /><br />It is quite easy to stay healthy and in shape when you are young. After age 35 it becomes much harder. <br /><br />With respect unless your body fat level was determined by Dual-energy X-ray Absortiometry there is no way you are 7% body fat. Caliper measurements and Bioelectric Impedence Analysis scales wildly inaccurate <br /><br />Body fat levels below 12% are uncommon even in elite professional male athletes (I know a national level middle distance runner who has 14% body fat with a BMI of only 20). Olympic marathoners are typically ~10% body fat. Anything below 10% is extremely rare.Brishttps://www.blogger.com/profile/05771534538377496202noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-5936255953263624482009-08-05T21:58:29.534-07:002009-08-05T21:58:29.534-07:00Starchy root vegetables are also great for my dige...Starchy root vegetables are also great for my digestion-- potatoes, sweet potatoes, taro, etc. It's all about texture. Chunks of fiber disturb my digestion, but I can tolerate a lot of fiber if the texture is smooth.Stephan Guyenethttps://www.blogger.com/profile/09218114625524777250noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-56574990877491676062009-08-05T21:54:38.028-07:002009-08-05T21:54:38.028-07:00I'll chime in with a little about myself. I w...I'll chime in with a little about myself. I went low-carb for a while about 2 years ago after reading "Good Calories, Bad Calories". I took to it fine, I felt good and I liked that I could skip meals no problem. <br /><br />Then "Nutrition and Physical Degeneration" began creeping back into my brain (it always comes back to Price), and I found the Kitava study, which caused my cognitive dissonance to boil over. I added back non-gluten carbs and I feel good. Not necessarily better or worse than I did on low-carb. I love fat and I think I could do well on practically nothing but fatty meat/organs with a couple of potatoes a day. But I can't afford it and besides, I don't think it's necessary.<br /><br />I do like how much more convenient it is to eat carbs. I feel hunger more than I did on low-carb, but I can still skip meals just fine. I'm probably eating about 52% fat, 35% carbohydrate, and 13% protein, but I never count. Roughly 3,500 calories a day. 5'9", 153 lbs, 7% body fat. That's 300 g carbs per day. I have no regard for glycemic index, I'll slam potatoes like the antidote's in them. My appetite goes way down when I'm not strength training, bike commuting, etc. <br /><br />About fiber. I hate to admit it, but my digestion is better with some amount of fiber. But the type is critical. Unsoaked beans and grains don't go over well. The best is ground, fermented and cooked whole grains like the brown rice dosas I make almost daily. Eating whole grains like cooked brown rice isn't great, but if the texture is fine from grinding it's much better. That type of fiber is great on my digestion, better than vegetables although they're fine too. That's my personal experience.Stephan Guyenethttps://www.blogger.com/profile/09218114625524777250noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-33474631003824438252009-08-05T21:40:50.756-07:002009-08-05T21:40:50.756-07:00Aaron a high fat diet very actively favours lactic...Aaron a high fat diet very actively favours lactic acid bacteria not putrefactive bacteria (which require carbohydrate). Liquid elemental diets containing 80% fat:20% protein with no carbs/fibre are currently being used to treat severe Irritable Bowel Disease. <br /><br />The colonocyte cells lining the colon only use volatile fatty acids for energy so they don't need (or want) any carbohydrate. <br /> <br />I have shared houses with vegetarians - without exception they produce absolutely putrid smelling stools - like a rotting pile of vegetables. My carnivore stools are small, firm and practically odourless .Brishttps://www.blogger.com/profile/05771534538377496202noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-72365260278185864962009-08-05T21:14:45.335-07:002009-08-05T21:14:45.335-07:00I am almost certainly insulin resistant from <2...I am almost certainly insulin resistant from <20g carbs/day. However I consider ketosis to be the natural state for mammals and to be embraced not avoided.<br /><br />Constipation is caused by insoluble fibre. The simplest treatment is to chew some sugarless gum as polyols are a great laxative.Brishttps://www.blogger.com/profile/05771534538377496202noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-82375927253573245622009-08-05T15:45:31.702-07:002009-08-05T15:45:31.702-07:00thanks for chiming in Kurt, I really value what yo...thanks for chiming in Kurt, I really value what you are trying to do with your blog.<br /><br />Sorry Stephan for getting a little off topic-- the quality of the discussions on here merit a private forum!<br /><br /><i> IR per se is not a disease - hyperinsulinemia and glycosylation are diseases and these phenomena are merely accompanied by IR in the metabolic syndrome. </i><br /><br />I agree with what you say-- but i want to see more studies done on healthy (non diseased people) to show if the byproducts of fat metabolism are more damaging over time vs carb metabolism (which may or may not be the case--) <br /><br />http://www.eurekalert.org/pub_releases/2007-12/cp-fdo112707.php<br /><br />the above study is interesting-- by increasing UPC1-- these mice are living longer-- a high fat diet by default would increase the number of mitochondria, and therefore, there would be overall increases in beta oxidation in the body-- especially on a low polyunsaturated fat diet -- because polyunsaturates increase uncoupling proteins (while saturated fats support beta oxidation). I wanna know if fat oxidation is more damaging than carb oxidation (remember, were talking about glucose here-- not fructose-- with the assumption that the body is going to store the carbs as glycogen in muscle-- and not convert the excess because of excess calories-- and we are considering a healthy metabolism)<br /><br />As per my condition-- i really don't get many bulging veins-- they are almost always caused by too much drinking, too many stimulants, too much stress, or in my case--diets extremely high in fat and low in carb (which i think has to be some kind of dopamine/serotonin issue going on)<br /><br />As per fiber, my stools have always been the best when i include some fruit, minimize vegetable intake, and include carbs in the form of stuff like buckwheat, barley, or root veggies.<br /><br />While on a high fat diet consisting of cream, butter,olive oil, meat,fish,and small amounts of fruit and veggies and almost no nuts-- after about a week or so, my stools because less well formed- and progress to stay that way for weeks-- it resolved itself with the addition of foods like the above (buckwheat potato, etc.)<br /><br />I don't think you need lots of fiber-- but i feel like it helps to have some. Fiber seems to do similar things for the body as adding probiotics to the mix.<br /><br />http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&DbFrom=PubMed&Cmd=Link&LinkName=pubmed_pubmed&LinkReadableName=Related%20Articles&IdsFromResult=1552366&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus<br /><br />I think the reason why you have to maintain a greater intake of probiotic type organisms on a higher fat diet is because fermentative bacteria seem to die out and get replaced by putrefactive bacteria-- and while i don't recommend a vegan diet to increase fermentative bacteria via fiber and low to no meat products-- fermentative bacteria do produce beneficial compounds for us: such as:<br /><br />Phenol and p-cresol concentrations in serum and daily outputs in urine significantly decline in cases of a fiber adequate diet-- or with the supplementation of probiotics<br /><br />the bacteria in my stomach may not care about me-- but I care about what they do for me<br /><br />heres an interesting study (even though its for a commercial product)<br /><br />http://www.ncbi.nlm.nih.gov/pubmed/8283290?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSumAaronhttps://www.blogger.com/profile/14565481105849556142noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-3005899266337004152009-08-05T13:24:28.345-07:002009-08-05T13:24:28.345-07:00Aaron
Peter refers to this as physiologic insulin...Aaron<br /><br />Peter refers to this as physiologic insulin resistance and it makes perfect sense to me. I speculate that this type of IR is completely different from the type that is pathologic and caused by chronic hyperinsulinemia and fructose. For one thing, it seems to be quickly reversible on the time scale of hours if not minutes.<br /><br />IR per se is not a disease - hyperinsulinemia and glycosylation are diseases and these phenomena are merely accompanied by IR in the metabolic syndrome.<br /><br />You also said:<br /><br />"Even with copious amounts of fiber and whole foods-- most people in my family are prone to hemorrhoids.<br />While i don't usually get huge ones-- on occasion, i can feel a bulge."<br /><br />You should very seriously consider that your hemorrhoids are actually caused by fiber and not be surprised that they are not amelioratied by it. (Personal and clinical experience)<br /><br />The lower your fiber and starch consumption, the more normal will be your colonic motility. You may be constipated for a few weeks until your colon adjusts, then it will be smooth sailing.<br /><br />Why do you care about feeding bacteria in your colon? They don't particularly care about you.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-75712190834674905422009-08-05T11:53:00.436-07:002009-08-05T11:53:00.436-07:00I'd like to clarify-- I never said Peter at hy...I'd like to clarify-- I never said Peter at hyperlipid "is" insulin resistant-- only that i fear that his diet may lead to it over time!<br /><br />I know he eats 20+ carbs a day (I worry when you are under this)-- in fact he eats in the range of 50 carbs a day-- way more sensible in my mind if you are doing low carb, high fat!<br /><br />In terms of his sat to mono ratio--- if you look at the fact that he eats a lot of cream and butter-- once you throw out the short chain fatty acids (which are totally beneficial in my mind-- his sat to mono ratio would be close to 1:1)<br /><br />My body runs well on starch-- and i don't seem to have all those microbial imbalances (Dysbiosis) that some low carb bloggers fear will happen from the fermentation of carbs. I eat carbs from sources that are low in mineral inhibiting substances. I see no problem with keeping your liver stacked with glycogen from fructose as long as you are not overdoing it!<br /><br />Once again-- my hunch is that an overreliance on fats for fuel would in fact over time cause mitochondria to pump out more waste material (in comparison to carbs)-- while most people would like to see the large increases in mitochondria from a high fat diet (i'm not so sure)-- you have to understand that using "any" fuel source has its drawbacks.<br /><br />As per a high fat diet messing up the adrenal glands-- I will let people in on my personal history. Even with copious amounts of fiber and whole foods-- most people in my family are prone to hemorrhoids.<br />While i don't usually get huge ones-- on occasion, i can feel a bulge.<br /><br />What is interesting here-- is that i usually get a slight bulge if i take carnitine- take stimulants, or go on a very high fat diet (i assume because all 3 promote fat burning!!). On all three things-- i feel energy and a wakefullness that makes it hard to sleep. I could eat fat all night and still not get that tired.<br /><br />As soon as i introduce more carbs to my diet-- my body relaxes-- i sleep better, my bulges go away-- that is my story-- high fat diets may affect others differently.Aaronhttps://www.blogger.com/profile/14565481105849556142noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-50979874354031522842009-08-05T10:19:22.166-07:002009-08-05T10:19:22.166-07:00Thanks randy and Bris. Peter claims he eats enoug...Thanks randy and Bris. Peter claims he eats enough carbs to stay out of ketosis, do you still think he is insulin resistant? Even if he is, it doesn't sound like it's the same kind of dangerous insulin resistance seen in metabolic syndrome, when the insulin receptors shut down due to excess insulin. With lower carbohydrates, the receptors down-regulate because they are not needed. Is the type of insulin resistance caused by extremely low carb diets easily reversed if necessary? Do you know where the "sweet spot" is (how many grams of carbohydrates to avoid either kind of IR)?<br /><br />I doubt my husband and I have to worry about this - we don't count calories or grams but we definitely are not up to 80% saturated fat or anywhere as low as under 20 grams of carbohydrate. <br /><br />Hopefully Stephan will write a post about high saturated fat diets and insulin resistance some day!Sentahttps://www.blogger.com/profile/02996306897347782114noreply@blogger.com