tag:blogger.com,1999:blog-1629175743855013102.post3443806065750522292..comments2024-03-28T11:29:46.845-07:00Comments on Whole Health Source: US Fructose Consumption TrendsStephan Guyenethttp://www.blogger.com/profile/09218114625524777250noreply@blogger.comBlogger9125tag:blogger.com,1999:blog-1629175743855013102.post-2935437199141502622009-12-13T05:57:13.292-08:002009-12-13T05:57:13.292-08:00Excellent new free full text online research deali...Excellent new free full text online research dealing the detrimental effects of HFCS and fructose. <br /><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673878/" rel="nofollow">Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans</a><br /><br /><i> (a) The increase in VAT in subjects consuming fructose and the increase in the expression of lipogenic genes in SAT in subjects consuming glucose suggest that fructose and glucose have differential effects on regional adipose distribution. We believe that these results are novel and warrant further investigation. <br /><br />(b) In addition to increases of postprandial TG and fasting and postprandial apoB, we show for what we believe is the first time that fructose consumption increases plasma concentrations of fasting sdLDL, oxidized LDL, and postprandial RLP-C and RLP-TG in older, overweight/obese men and women, whereas glucose consumption does not. These changes may be associated with increased risk of cardiovascular disease.<br /> <br />(c) Fructose consumption increased hepatic fractional DNL, and postprandial LPL activity was lower in subjects consuming fructose compared with those consuming glucose. These results suggest that both increased DNL and decreased LPL-mediated clearance contribute to fructose-induced postprandial hypertriglyceridemia. <br /><br />(d) Consumption of fructose at 25% of energy requirements with an ad libitum diet decreased glucose tolerance and insulin sensitivity in older overweight/obese adults compared with glucose consumption.<br /><br /> (e) VAT accumulation and increases of 24-hour TG exposure, peak postprandial TG concentrations, and postprandial RLP-C concentrations in response to fructose consumption were more pronounced in men than in women. Consumption of sugar-sweetened beverages resulted in greater decreases in insulin sensitivity in women than in men.</i>TedHutchinsonhttps://www.blogger.com/profile/13140097526458431747noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-91810270625163931222008-05-20T22:46:00.000-07:002008-05-20T22:46:00.000-07:00Hi Ronald, You're right, Taubes doesn't really po...Hi Ronald,<BR/><BR/> You're right, Taubes doesn't really point the finger at HFCS. Don't get me wrong, I don't think fructose is THE culprit. Actually, I'm less convinced than ever after seeing that it's only increased by 20%. Although I will say that it's a hell of a correlation that HFCS consumption has increased by 700% in the same time period as the obesity epidemic explosion.<BR/><BR/>But I still think it has the potential to be a major contributor to health problems. The epidemic of nonalcoholic steatohepatitis (fatty liver) that's affecting the overweight in Amercia may have something to do with fructose. Overfeeding rats with fructose causes steatohepatitis. Once your liver is foie gras, you can forget about having good insulin sensitivity. I think it's all tied together.<BR/><BR/>Average fructose statistics also hide the fact that some people consume massive amounts of it in the form of soda, while others consume virtually none. <BR/><BR/>I think too much sugar is unhealthy, but it's probably not sufficient to cause massive metabolic problems without the aid of other problematic foods. The Kuna eat their fair share of sugar.Stephan Guyenethttps://www.blogger.com/profile/09218114625524777250noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-38886443048863197612008-05-20T22:09:00.000-07:002008-05-20T22:09:00.000-07:00The author of Good Calories Bad Calories was think...The author of Good Calories Bad Calories was thinking HFCS was a major cause of obesity when he started research, but he no longer believes that. It seems that it was more trying to cut down on dietary fat, and eating quite a lot more carbs as a result.Ronald Pottolhttps://www.blogger.com/profile/12052424704490061291noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-91218733739266654292008-05-20T17:17:00.000-07:002008-05-20T17:17:00.000-07:00That's about what I'm thinking as well.That's about what I'm thinking as well.Stephan Guyenethttps://www.blogger.com/profile/09218114625524777250noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-53220575218812567702008-05-20T17:00:00.000-07:002008-05-20T17:00:00.000-07:00"Crack an egg? Um, what's an egg?" - Average Amer..."Crack an egg? Um, what's an egg?" - Average American<BR/><BR/>It sounds like the detrimental changes to our diet you're describing have arrived en masse -- increased fructose, sucrose, vegetable oil, wheat, chemical pollutants, processed foods and additives, etc. <BR/><BR/>Perhaps our bodies could have handled an increase in one such ingredient, but the combined effect overwhelms and shuts down the systems we have in place to compensate and regulate. Maybe HFCS/fructose is such a problem partly because of everything else we're eating, and partly because it's substantially detrimental enough to push us far past the tipping point.Debshttps://www.blogger.com/profile/09217281333751656056noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-88443561605761442102008-05-20T09:55:00.000-07:002008-05-20T09:55:00.000-07:00Well then I suppose the HFCS stands out. Do New Z...Well then I suppose the HFCS stands out. Do New Zealanders eat a lot of trans fat? <BR/><BR/>Oh yeah, egg beaters. That stuff is a crime against humanity. It's basically egg whites in a carton. It's more for getting rid of the cholesterol in the yolks than for convenience. I guess nobody told them egg yolks don't raise serum cholesterol...Stephan Guyenethttps://www.blogger.com/profile/09218114625524777250noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-77102176130004555252008-05-20T03:53:00.000-07:002008-05-20T03:53:00.000-07:00I'm not sure I can assess NZers' diets objectively...I'm not sure I can assess NZers' diets objectively--My own diet since leaving home has bounced around between several extremes.<BR/><BR/>My guess would be that middle-class NZ families eat much like middle-class families in most other "Western" countries (US, Canada, Aus, NZ, Britain, etc.) with perhaps a bit less processed food. <BR/><BR/>For instance, I had never heard of "egg beaters" before a few weeks ago and was kind of amazed that such a product exists (people can't crack an egg?).^https://www.blogger.com/profile/14209117357558394101noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-36515972340262467282008-05-18T22:06:00.000-07:002008-05-18T22:06:00.000-07:00Hi Chainey, I agree that the difference in fructo...Hi Chainey,<BR/><BR/> I agree that the difference in fructose between sucrose and HFCS isn't very large. I just looked at the sweetener consumption stats for New Zealand and they're similar to the US. The Kuna also eat a fair amount of sugar and are healthy. So basically, I agree that the relationship is murky.<BR/><BR/>My guess is that fructose is probably not sufficient by itself to cause major problems, but acts synergistically with other elements of the diet to cause metabolic problems.<BR/><BR/>Do New Zealanders eat much processed food, or is it mostly homemade? Do they eat mostly animal or vegetable fats? Full-fat or low-fat milk? Do they eat a lot of wheat, and if so, in what form? If it's bread, does it tend to be sourdough?<BR/><BR/>We're going to get to the bottom of this!Stephan Guyenethttps://www.blogger.com/profile/09218114625524777250noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-78131911283205597912008-05-18T00:22:00.000-07:002008-05-18T00:22:00.000-07:00I've pondered this a bit myself. The HFCS thing se...I've pondered this a bit myself. The HFCS thing seems a bit hard to pin down in that it's only <I>marginally</I> more fructose than ordinary sugar.<BR/><BR/>In New Zealand, where I live, morbid obesity is rare. Sure, "middle-aged spread" is common, including at my place, but the "epidemic" that I keep hearing about from the US is yet to reach our shores in its most virulent form. <BR/><BR/>Yet we eat plenty of sugar, and I have all my life. HFCS is not a major feature though since we don't produce or import much corn and cane sugar is readily available from, for instance, Fiji.<BR/><BR/>So that leads us back to HFCS as prime suspect for the US problem, but at only 5% more fructose ...?<BR/><BR/>Anyway, it doesn't seem to add up..^https://www.blogger.com/profile/14209117357558394101noreply@blogger.com