tag:blogger.com,1999:blog-1629175743855013102.post4412063852221837009..comments2024-03-27T23:47:41.656-07:00Comments on Whole Health Source: Diabetes and Your Small IntestineStephan Guyenethttp://www.blogger.com/profile/09218114625524777250noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-1629175743855013102.post-81736913876210723892009-10-07T12:40:17.254-07:002009-10-07T12:40:17.254-07:00Stephan,
I don't know if you still look at co...Stephan,<br /><br />I don't know if you still look at comments from these old posts, but something in this one keeps nagging at me. I've been reading Taubes' GCBC, and he builds up a case for insulin as the primary driver of obesity. And yet according to the study you cited:<br /><br />"Compared to controls losing an equivalent amount of weight on a low-calorie diet, the bypass patients saw a HUGE increase in their oral glucose tolerance test (OGTT) GLP-1 secretion (9.8 vs 112.5 pmol/L), a large increase in GIP secretion, and a corresponding increase in insulin secretion (575 vs 769 pmol/L)."<br /><br />So improved glucose control came at the expense of higher insulin levels, which would seem to be a headwind for individuals who had undergone bypass to lose weight. Or is there also something else going on with respect to fat metabolism if the upper GI is bypassed? Interesting.Unknownhttps://www.blogger.com/profile/11663414347144901156noreply@blogger.comtag:blogger.com,1999:blog-1629175743855013102.post-8888253710516395732009-09-29T11:34:11.817-07:002009-09-29T11:34:11.817-07:00Even though this is an old post, I saw 0 comments ...Even though this is an old post, I saw 0 comments and just couldn't resist.<br /><br />I think your posts on diabetes, fatty liver, etc., are very interesting because I think finding out exactly what is happening in these case cases is central to a better understanding of human metabolism in general. I don't understand what keeps most doctors from widening their view and using what they know of the diabetes disease process as a basis for suggesting that all of their patients reduce their sugar intake drastically. It seems to me that the evidence that sugar is bad for us is much less ambivalent than the supposed evidence that saturated fat is bad for us, and yet they have not problem telling patients (even diabetics!) to reduce their saturated fat intake. If they are not satisfying their palate with the richness of fatty foods, what are they going to eat more of? Sugar, of course.Unknownhttps://www.blogger.com/profile/11663414347144901156noreply@blogger.com